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Amy Schumer Opens Up About Weight Loss Success with New Medication

Published March 25, 2025

After struggling with previous weight loss attempts, Amy Schumer says she’s finally found a solution that works for her—thanks to a combination of hormone therapy and the GLP-1 drug Mounjaro.

A New Approach After Wegovy Woes

The comedian, 42, previously tried Wegovy, another medication used for weight loss, but had a bad reaction that left her vomiting. Now, she’s taking Mounjaro, a drug originally designed for type 2 diabetes that’s also known to aid in weight loss.

RELATED: Amy Schumer Reveals She Has Cushing Syndrome

Alongside this, Schumer was prescribed estrogen and progesterone for her perimenopause symptoms—and the results have been life-changing.

Feeling Better Than Ever

Speaking candidly in a recent video post, Schumer said the benefits have gone far beyond just weight loss:
✅ More energy
✅ Fuller hair & better skin
✅ Improved sex drive (she made sure to clarify: "I'm talking about sex!")

Schumer’s journey highlights how hormone balance and proper medication can greatly affect overall well-being. And judging by her humour and confidence, she’s feeling better than ever.

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